DNA-BAR: distinguisher selection for DNA barcoding

被引：37

作者：

DasGupa, B

Konwar, KM

Mandoiu, II ^{[1
]}

Shvartsman, AA

机构：

[1] Univ Illinois, Dept Comp Sci, Chicago, IL 60607 USA

[2] Univ Connecticut, Dept Comp Sci & Engn, Storrs, CT 06269 USA

来源：

BIOINFORMATICS | 2005年 / 21卷 / 16期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1093/bioinformatics/bti547

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism. Selected distinguishers satisfy user specified bounds on length, melting temperature and GC content, as well as redundancy and cross-hybridization constraints.

引用

页码：3424 / 3426

页数：3

共 7 条

[1] Universal DNA tag systems: A combinatorial design scheme [J].