Immunobiological Properties of Yersinia pestis Antigens

被引：2

作者：

Byvalov, A. A. ^{[1
]}

Ovodov, Yu. S. ^{[1
]}

机构：

[1] Russian Acad Sci, Urals Branch, Komi Sci Ctr, Inst Physiol, Syktyvkar 167982, Russia

来源：

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY | 2011年 / 37卷 / 04期

关键词：

Yersinia pestis; antigen; pathogenicity; protectiveness; immunity; RECOMBINANT V-ANTIGEN; OUTER-MEMBRANE PROTEINS; PASTEURELLA-PESTIS; BUBONIC PLAGUE; PNEUMONIC PLAGUE; PATHOGENIC YERSINIAE; PROVIDES PROTECTION; VIRULENCE PLASMID; IMMUNE-RESPONSE; CAUSATIVE AGENT;

D O I：

10.1134/S1068162011040042

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The immunobiological properties of plague microbe antigens are described in the review. All of the identified antigens are evaluated in relation to the pathogenicity of Yersinia pestis (resistance to phagocytosis, toxicity, adhesiveness, etc.), as well as persistence ability and adaptation to a variable environment. In addition, the role of the antigen in the immunogenicity of a living plague microbe and literature data about the inherent protectiveness of antigens for the model animals are discussed. The data concerning the mechanisms of antigenic contribution to the development of the adaptive immunity are presented.

引用

页码：400 / 410

页数：11

共 116 条

[1]

Deletion of Braun lipoprotein gene (lpp) and curing of plasmid pPCP1 dramatically alter the virulence of Yersinia pestis CO92 in a mouse model of pneumonic plague [J].

Agar, Stacy L. ;

Sha, Jian ;

Baze, Wallace B. ;

Erova, Tatiana E. ;

Foltz, Sheri M. ;

Suarez, Giovanni ;

Wang, Shaofei ;

Chopra, Ashok K. .

MICROBIOLOGY-SGM, 2009, 155 :3247-3259

[2]

Recombinant V antigen protects mice against pneumonic and bubonic plague caused by F1-capsule-positive and -negative strains of Yersinia pestis [J].

Anderson, GW ;

Leary, SEC ;

Williamson, ED ;

Titball, RW ;

Welkos, SL ;

Worsham, PL ;

Friedlander, AM .

INFECTION AND IMMUNITY, 1996, 64 (11) :4580-4585

[3]

Protective efficacy of recombinant Yersinia outer proteins against bubonic plague caused by encapsulated and nonencapsulated Yersinia pestis [J].

Andrews, GP ;

Strachan, ST ;

Benner, GE ;

Sample, AK ;

Anderson, GW ;

Adamovicz, JJ ;

Welkos, SL ;

Pullen, JK ;

Friedlander, AM .

INFECTION AND IMMUNITY, 1999, 67 (03) :1533-1537

[4]

Anisimov A. P., 2002, Molekulyarnaya Genetika Mikrobiologiya i Virusologiya, P3

[5]

The subcutaneous inoculation of pH 6 antigen mutants of Yersinia pestis does not affect virulence and immune response in mice [J].

Anisimov, Andrey P. ;

Bakhteeva, Irina V. ;

Panfertsev, Evgeniy A. ;

Svetoch, Tat'yana E. ;

Kravchenko, Tat'yana B. ;

Platonov, Mikhail E. ;

Titareva, Galina M. ;

Kombarova, Tat'yana I. ;

Ivanov, Sergey A. ;

Rakin, Alexander V. ;

Amoako, Kingsley K. ;

Dentovskaya, Svetlana V. .

JOURNAL OF MEDICAL MICROBIOLOGY, 2009, 58 (01) :26-36

[6]

Intraspecific diversity of Yersinia pestis [J].

Anisimov, AP ;

Lindler, LE ;

Pier, GB .

CLINICAL MICROBIOLOGY REVIEWS, 2004, 17 (02) :434-+

[7]

BAKER EE, 1952, J IMMUNOL, V68, P131

[8]

BAKER EE, 1947, P SOC EXP BIOL MED, V64, P139, DOI 10.3181/00379727-64-15726

[9]

Bakhrakh E.E., 1962, ZH MIKROBIOL EPIDEMI, P126

[10]

BAKHRAKH EE, 1972, ZH MIKROB EPID IMMUN, P101

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