Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors

被引:118
作者
Liao, Jing [1 ]
Wu, Zhao [1 ]
Wang, Ying [1 ]
Cheng, Lu [1 ]
Cui, Chun [1 ]
Gao, Yuan [1 ]
Chen, Taotao [1 ]
Rao, Lingjun [1 ]
Chen, Siye [1 ]
Jia, Nannan [1 ]
Dai, Huiming [1 ]
Xin, Shunmei [1 ]
Kang, Jiuhong [1 ]
Pei, Gang [1 ]
Xiao, Lei [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Mol Cell Biol Lab,Key Lab Stem Cell Biol, Shanghai 200031, Peoples R China
关键词
D O I
10.1038/cr.2008.51
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:600 / 603
页数:4
相关论文
共 10 条
[1]   Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells [J].
Cowan, CA ;
Atienza, J ;
Melton, DA ;
Eggan, K .
SCIENCE, 2005, 309 (5739) :1369-1373
[2]  
Cowan CA, 2004, NEW ENGL J MED, V350, P1353, DOI 10.1056/NEJMsr040330
[3]  
Park IH, 2008, NATURE, V451, P141, DOI 10.1038/natureO6534
[4]   The magic of four: induction of pluripotent stem cells from somatic cells by Oct4, Sox2, Myc and Klf4 [J].
Qi, Huayu ;
Pei, Duanqing .
CELL RESEARCH, 2007, 17 (07) :578-580
[5]   Induction of pluripotent stem cells from adult human fibroblasts by defined factors [J].
Takahashi, Kazutoshi ;
Tanabe, Koji ;
Ohnuki, Mari ;
Narita, Megumi ;
Ichisaka, Tomoko ;
Tomoda, Kiichiro ;
Yamanaka, Shinya .
CELL, 2007, 131 (05) :861-872
[6]   Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors [J].
Takahashi, Kazutoshi ;
Yamanaka, Shinya .
CELL, 2006, 126 (04) :663-676
[7]   Embryonic stem cell lines derived from human blastocysts [J].
Thomson, JA ;
Itskovitz-Eldor, J ;
Shapiro, SS ;
Waknitz, MA ;
Swiergiel, JJ ;
Marshall, VS ;
Jones, JM .
SCIENCE, 1998, 282 (5391) :1145-1147
[8]   Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells [J].
Xiao, Lei ;
Yuan, Xuan ;
Sharkis, Saul J. .
STEM CELLS, 2006, 24 (06) :1476-1486
[9]   Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells [J].
Xu, RH ;
Peck, RM ;
Li, DS ;
Feng, XZ ;
Ludwig, T ;
Thomson, JA .
NATURE METHODS, 2005, 2 (03) :185-190
[10]   Induced pluripotent stem cell lines derived from human somatic cells [J].
Yu, Junying ;
Vodyanik, Maxim A. ;
Smuga-Otto, Kim ;
Antosiewicz-Bourget, Jessica ;
Frane, Jennifer L. ;
Tian, Shulan ;
Nie, Jeff ;
Jonsdottir, Gudrun A. ;
Ruotti, Victor ;
Stewart, Ron ;
Slukvin, Igor I. ;
Thomson, James A. .
SCIENCE, 2007, 318 (5858) :1917-1920