Cancer-susceptibility genes - Gatekeepers and caretakers

被引:842
作者
Kinzler, KW [1 ]
Vogelstein, B [1 ]
机构
[1] JOHNS HOPKINS UNIV,HOWARD HUGHES MED INST,BALTIMORE,MD 21231
关键词
D O I
10.1038/386761a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:761 / &
页数:2
相关论文
共 12 条
  • [1] Transcriptional activation by BRCA1
    Chapman, MS
    Verma, IM
    [J]. NATURE, 1996, 382 (6593) : 678 - 679
  • [2] The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse
    Hakem, R
    delaPompa, JL
    Sirard, C
    Mo, R
    Woo, M
    Hakem, A
    Wakeham, A
    Potter, J
    Reitmair, A
    Billia, F
    Firpo, E
    Hui, CC
    Roberts, J
    Rossant, J
    Mak, TW
    [J]. CELL, 1996, 85 (07) : 1009 - 1023
  • [3] THE SEARCH FOR THE RIGHT PARTNER - HOMOLOGOUS PAIRING AND DNA STRAND EXCHANGE PROTEINS IN EUKARYOTES
    HEYER, WD
    [J]. EXPERIENTIA, 1994, 50 (03): : 223 - 233
  • [4] Growth retardation and tumour inhibition by BRCA1
    Holt, JT
    Thompson, ME
    Szabo, C
    RobinsonBenion, C
    Arteaga, CL
    King, MC
    Jensen, RA
    [J]. NATURE GENETICS, 1996, 12 (03) : 298 - 302
  • [5] Lessons from hereditary colorectal cancer
    Kinzler, KW
    Vogelstein, B
    [J]. CELL, 1996, 87 (02) : 159 - 170
  • [6] Hereditary cancer: Two hits revisited
    Knudson, AG
    [J]. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1996, 122 (03) : 135 - 140
  • [7] Lim DS, 1996, MOL CELL BIOL, V16, P7133
  • [8] Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development
    Liu, CY
    FleskenNikitin, A
    Li, S
    Zeng, YY
    Lee, WH
    [J]. GENES & DEVELOPMENT, 1996, 10 (14) : 1835 - 1843
  • [9] Transcriptional activation functions in BRCA2
    Milner, J
    Ponder, B
    HughesDavies, L
    Seltmann, M
    Kouzarides, T
    [J]. NATURE, 1997, 386 (6627) : 772 - 773
  • [10] Evidence for a transcriptional activation function of BRCA1 C-terminal region
    Monteiro, ANA
    August, A
    Hanafusa, H
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (24) : 13595 - 13599