SHRiMP2: Sensitive yet Practical Short Read Mapping

被引：237

作者：

David, Matei ^{[1
]}

Dzamba, Misko ^{[2
]}

Lister, Dan ^{[2
]}

Ilie, Lucian ^{[3
]}

Brudno, Michael ^{[2
,4
]}

机构：

[1] Princeton Univ, Dept Comp Sci, Princeton, NJ 08544 USA

[2] Univ Toronto, Dept Comp Sci, Toronto, ON M5S 1A1, Canada

[3] Univ Western Ontario, Dept Comp Sci, London, ON N6A 3K7, Canada

[4] Univ Toronto, Donnelly Ctr, Toronto, ON M5S 1A1, Canada

来源：

BIOINFORMATICS | 2011年 / 27卷 / 07期

关键词：

ALIGNMENT;

D O I：

10.1093/bioinformatics/btr046

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We report on a major update (version 2) of the original SHort Read Mapping Program (SHRiMP). SHRiMP2 primarily targets mapping sensitivity, and is able to achieve high accuracy at a very reasonable speed. SHRiMP2 supports both letter space and color space (AB/SOLiD) reads, enables for direct alignment of paired reads and uses parallel computation to fully utilize multi- core architectures.

引用

页码：1011 / 1012

页数：2

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