Lack of Transmission among Close Contacts of Patient with Imported Case of Middle East Respiratory Syndrome into the United States, 2014

被引:16
作者
Breakwell, Lucy [1 ]
Pringle, Kimberly [1 ]
Chea, Nora [1 ]
Allen, Donna [2 ]
Allen, Steve [2 ]
Richards, Shawn [2 ]
Pantones, Pam [2 ]
Sandoval, Michelle [1 ,2 ]
Liu, Lixia [2 ]
Vernon, Michael [3 ]
Conover, Craig [4 ]
Chugh, Rashmi [5 ]
DeMaria, Alfred [6 ]
Burns, Rachel [6 ]
Smole, Sandra [6 ]
Gerber, Susan I. [1 ]
Cohen, Nicole J. [1 ]
Kuhar, David [1 ]
Haynes, Lia M. [1 ]
Schneider, Eileen [1 ]
Kumar, Alan [7 ]
Kapoor, Minal [7 ]
Madrigal, Marlene [7 ]
Swerdlow, David L. [1 ]
Feikin, Daniel R. [1 ]
机构
[1] Ctr Dis Control & Prevent, Atlanta, GA 30329 USA
[2] Indiana State Dept Hlth, Indianapolis, IN 46202 USA
[3] Cook Cty Dept Publ Hlth, Oak Forest, IL USA
[4] Illinois Dept Publ Hlth, Chicago, IL USA
[5] DuPage Cty Hlth Dept, Wheaton, IL USA
[6] Massachusetts Dept Publ Hlth, Jamaica Plain, MA USA
[7] Community Hosp, Munster, IN USA
关键词
CORONAVIRUS MERS-COV; FAMILY CLUSTER; OUTBREAK; INFECTIONS; SARS;
D O I
10.3201/eid2107.150054
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
071005 [微生物学]; 100108 [医学免疫学];
摘要
In May 2014, a traveler from the Kingdom of Saudi Arabia was the first person identified with Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the United States. To evaluate transmission risk, we determined the type, duration, and frequency of patient contact among health care personnel (HCP), household, and community contacts by using standard questionnaires and, for HCP, global positioning system (GPS) tracer tag logs. Respiratory and serum samples from all contacts were tested for MERS-CoV. Of 61 identified contacts, 56 were interviewed. HCP exposures occurred most frequently in the emergency department (69%) and among nurses (47%); some HCP had contact with respiratory secretions. Household and community contacts had brief contact (e.g., hugging). All laboratory test results were negative for MERS-CoV. This contact investigation found no secondary cases, despite case-patient contact by 61 persons, and provides useful information about MERS-CoV transmission risk. Compared with GPS tracer tag recordings, self-reported contact may not be as accurate.
引用
收藏
页码:1128 / 1134
页数:7
相关论文
共 27 条
[1]
Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections, Tunisia, 2013 [J].
Abroug, Fekri ;
Slim, Amine ;
Ouanes-Besbes, Lamia ;
Kacem, Mohamed-Ali Hadj ;
Dachraoui, Fahmi ;
Ouanes, Islem ;
Lu, Xiaoyan ;
Tao, Ying ;
Paden, Clinton ;
Caidi, Hayat ;
Miao, Congrong ;
Al-Hajri, Mohammed Mohammed ;
Zorraga, Mokhtar ;
Ghaouar, Wissem ;
BenSalah, Afif ;
Gerber, Susan I. .
EMERGING INFECTIOUS DISEASES, 2014, 20 (09) :1527-1530
[2]
Hospital-Associated Outbreak of Middle East Respiratory Syndrome Coronavirus: A Serologic, Epidemiologic, and Clinical Description [J].
Al-Abdallat, Mohammad Mousa ;
Payne, Daniel C. ;
Alqasrawi, Sultan ;
Rha, Brian ;
Tohme, Rania A. ;
Abedi, Glen R. ;
Al Nsour, Mohannad ;
Iblan, Ibrahim ;
Jarour, Najwa ;
Farag, Noha H. ;
Haddadin, Aktham ;
Al-Sanouri, Tarek ;
Tamin, Azaibi ;
Harcourt, Jennifer L. ;
Kuhar, David T. ;
Swerdlow, David L. ;
Erdman, Dean D. ;
Pallansch, Mark A. ;
Haynes, Lia M. ;
Gerber, Susan I. .
CLINICAL INFECTIOUS DISEASES, 2014, 59 (09) :1225-1233
[3]
Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus [J].
Assiri, Abdullah ;
McGeer, Allison ;
Perl, Trish M. ;
Price, Connie S. ;
Al Rabeeah, Abdullah A. ;
Cummings, Derek A. T. ;
Alabdullatif, Zaki N. ;
Assad, Maher ;
Almulhim, Abdulmohsen ;
Makhdoom, Hatem ;
Madani, Hossam ;
Alhakeem, Rafat ;
Al-Tawfiq, Jaffar A. ;
Cotten, Matthew ;
Watson, Simon J. ;
Kellam, Paul ;
Zumla, Alimuddin I. ;
Memish, Ziad A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (05) :407-416
[4]
Bialek SR, 2014, MMWR-MORBID MORTAL W, V63, P431
[5]
Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk [J].
Breban, Romulus ;
Riou, Julien ;
Fontanet, Arnaud .
LANCET, 2013, 382 (9893) :694-699
[6]
Middle East Respiratory Syndrome Coronavirus Quasispecies That Include Homologues of Human Isolates Revealed through Whole-Genome Analysis and Virus Cultured from Dromedary Camels in Saudi Arabia [J].
Briese, Thomas ;
Mishra, Nischay ;
Jain, Komal ;
Zalmout, Iyad S. ;
Jabado, Omar J. ;
Karesh, William B. ;
Daszak, Peter ;
Mohammed, Osama B. ;
Alagaili, Abdulaziz N. ;
Lipkin, W. Ian .
MBIO, 2014, 5 (03)
[7]
Buchholz U, 2013, EUROSURVEILLANCE, V18, P6
[8]
Devi JP, 2014, EUROSURVEILLANCE, V19, P2
[9]
GULLAND A, 2013, BMJ-BRIT MED J, V346, P28991, DOI DOI 10.1136/BMJ.F3114
[10]
Clinical and Laboratory Findings of the First Imported Case of Middle East Respiratory Syndrome Coronavirus to the United States [J].
Kapoor, Minal ;
Pringle, Kimberly ;
Kumar, Alan ;
Dearth, Stephanie ;
Liu, Lixia ;
Lovchik, Judith ;
Perez, Omar ;
Pontones, Pam ;
Richards, Shawn ;
Yeadon-Fagbohun, Jaime ;
Breakwell, Lucy ;
Chea, Nora ;
Cohen, Nicole J. ;
Schneider, Eileen ;
Erdman, Dean ;
Haynes, Lia ;
Pallansch, Mark ;
Tao, Ying ;
Tong, Suxiang ;
Gerber, Susan ;
Swerdlow, David ;
Feikin, Daniel R. .
CLINICAL INFECTIOUS DISEASES, 2014, 59 (11) :1511-1518