Covalently induced activation of the δ opioid receptor by a fluorogenic affinity label, 7′-(phthalaldehyde-carboxamido)naltrindole (PNTI)

被引：10

作者：

Le Bourdonnec, B

El Kouhen, R

Poda, G

Law, PY

Loh, HH

Ferguson, DM

Portoghese, PS ^{[1
]}

机构：

[1] Univ Minnesota, Coll Pharm, Dept Med Chem, Minneapolis, MN 55455 USA

[2] Univ Minnesota, Sch Med, Dept Pharmacol, Minneapolis, MN 55455 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 2001年 / 44卷 / 07期

关键词：

D O I：

10.1021/jm010004u

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1017 / 1020

页数：4

共 27 条

[1] ALVAREZCOQUE MCG, 1989, ANAL BIOCHEM, V178, P1
[2] Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety
Ananthan, S
Johnson, CA
Carter, RL
Clayton, SD
Rice, KC
Xu, H
Davis, P
Porreca, F
Rothman, RB
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (15) : 2872 - 2881
[3] Conformational changes in rhodopsin - Movement of helix F detected by site-specific chemical labeling and fluorescence spectroscopy
Dunham, TD
Farrens, DL
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (03) : 1683 - 1690
[4] Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin
Farrens, DL
Altenbach, C
Yang, K
Hubbell, WL
Khorana, HG
[J]. SCIENCE, 1996, 274 (5288) : 768 - 770
[5] FOURNIEZALUSKI MC, 1981, MOL PHARMACOL, V20, P484
[6] Hasbi A, 2000, J PHARMACOL EXP THER, V293, P237
[7] NEW EXAMPLE OF A MORPHINE-SENSITIVE NEURO-EFFECTOR JUNCTION - ADRENERGIC TRANSMISSION IN MOUSE VAS-DEFERENS
HENDERSON, G
HUGHES, J
KOSTERLITZ, HW
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1972, 46 (04) : 764 - 766
[8] Constitutive activation of the beta(2) adrenergic receptor alters the orientation of its sixth membrane-spanning segment
Javitch, JA
Fu, DY
Liapakis, G
Chen, JY
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (30) : 18546 - 18549
[9] Visualization of time-dependent redistribution of δ-opioid receptors in neuronal cells during prolonged agonist exposure
Ko, JL
Arvidsson, U
Williams, FG
Law, PY
Elde, R
Loh, HH
[J]. MOLECULAR BRAIN RESEARCH, 1999, 69 (02): : 171 - 185
[10] Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor
Konopka, JB
Margarit, SM
Dube, P
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (13) : 6764 - 6769

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