Cytomegalovirus infection and Guillain-Barre syndrome: The clinical, electrophysiologic, and prognostic features

被引：165

作者：

Visser, LH ^{[1
]}

vanderMeche, FGA ^{[1
]}

Meulstee, J ^{[1
]}

Rothbarth, PP ^{[1
]}

Jacobs, BC ^{[1
]}

Schmitz, PIM ^{[1
]}

vanDoorn, PA ^{[1
]}

机构：

[1] ERASMUS UNIV ROTTERDAM,ROTTERDAM,NETHERLANDS

来源：

NEUROLOGY | 1996年 / 47卷 / 03期

关键词：

D O I：

10.1212/WNL.47.3.668

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Guillain-Barre syndrome (GBS) is usually preceded by infections, in particular cytomegalovirus (CMV) and Campylobacter jejuni infection. We studied the clinical and electrophysiologic features of 20 CMV-associated GBS patients and compared the findings with earlier established data of C. jejuni-related GBS patients (n = 43) and of GBS patients without these infections (n = 71). The patients all participated in the Dutch GBS trial in which we compared the effect of intravenous immune globulins and plasma exchange. We demonstrate that CMV-related GBS patients have a different clinical pattern in comparison with the other two GBS groups. They are significantly younger, initially have a severe course indicated by a high frequency of respiratory insufficiency, and often develop cranial nerve involvement and severe sensory loss. This is in contrast to C. jejuni infection, which is associated with motor GBS. Both infections are associated with delayed recovery compared with the GBS patients without these infections.

引用

页码：668 / 673

页数：6

共 24 条

[1]

[Anonymous], 1978, Ann Neurol, V3, P565

[2] ASSESSMENT OF CURRENT DIAGNOSTIC-CRITERIA FOR GUILLAIN-BARRE-SYNDROME [J].