Cortically induced thalamic plasticity in the primate somatosensory system

被引：126

作者：

Ergenzinger, ER

Glasier, MM

Hahm, JO

Pons, TP ^{[1
]}

机构：

[1] Wake Forest Univ, Sch Med, Dept Neurosurg, Winston Salem, NC 27127 USA

[2] Wake Forest Univ, Sch Med, Program Neurosci, Winston Salem, NC 27127 USA

[3] Georgetown Univ, Dept Neurosurg, Washington, DC 20057 USA

来源：

NATURE NEUROSCIENCE | 1998年 / 1卷 / 03期

关键词：

D O I：

10.1038/673

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The influence of cortical feedback on receptive field organization in the thalamus was assessed in the primate somatosensory system. Chronic and acute suppression of neuronal activity in primary somatosensory cortex resulted in a striking enlargement of receptive fields in the ventroposterior thalamus. This finding demonstrates a dramatic 'top-down' influence of cortex on receptive field size in the somatosensory thalamus. In addition, this result has important implications for studies of adult neuronal plasticity because it indicates that changes in 'higher-order' areas of the brain can trigger extensive changes in the receptive field characteristics of neurons located earlier in the processing pathway.

引用

页码：226 / 229

页数：4

共 26 条

[1]

BAVA A, 1968, ARCH ITAL BIOL, V106, P204

[2] CORTICOFUGAL INFLUENCE UPON CAT THALAMIC VENTROBASAL COMPLEX [J].