The Whitewater Arroyo virus: Natural evidence for genetic recombination among Tacaribe serocomplex viruses (family Arenaviridae)

被引：54

作者：

Charrel, RN

de Lamballerie, X

Fulhorst, CF

机构：

[1] Univ Texas, Med Branch, Dept Pathol, Galveston, TX 77555 USA

[2] Univ Texas, Med Branch, Ctr Trop Dis, Galveston, TX 77555 USA

[3] Fac Med Marseille, Lab Virol Mol Trop & Tranfusionnelle, Unite Virus Emergents, F-13005 Marseille, France

来源：

VIROLOGY | 2001年 / 283卷 / 02期

关键词：

arenavirus; Whitewater Arroyo virus; Pirital virus; genetic recombination; evolution;

D O I：

10.1006/viro.2001.0874

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The Tacarlbe serocomplex (family Arenaviridae) comprises three phylogenetic lineages, designated A, B, and C. The sequence of a 3278-nt fragment of the small genomic segment of the Whitewater Arroyo (WWA) Virus was determined to extend our knowledge on the phylogenetic relationship of this newly discovered North American Tacaribe complex virus to other arenaviruses. Independent analyses of full-length nucleoprotein (N) and glycoprotein precursor (GPC) amino acid sequences indicated that the WWA virus N and GPC genes are descended from a lineage A virus and lineage B virus, respectively. The different phylogenetic histories of the N and GPC genes indicate that the WWA virus genome is a product of recombination between two Tacaribe complex viruses, (C) 2001 Academic Press.

引用

页码：161 / 166

页数：6

共 21 条

[1] THE SEQUENCES OF THE N-PROTEIN GENE AND INTERGENIC REGION OF THE S-RNA OF PICHINDE ARENAVIRUS [J].