Large genomic differences explain our little quirks

被引:3
作者
Check, E
机构
关键词
D O I
10.1038/435252b
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Everybody shares 99% of our DNA with all the other people on earth. At the annual Genome meeting in New York new information was revealed about human diversity. The idea that our genomes had the same basic structure, number of genes, in roughly the same order and a few differences in the DNA base sequences.. Researches have found that some of us have more copies of a certain gene with a varying number of deletions, insertions and major re-arrangements in our genomes.. At least 297 places in the genome have been identified where there are structural variations.. These structural differences are important in human evolution. Natural selection is working on these genes. These genes belong to groups that help us interact with the environment and might explain why some people react in different ways to the same outside influence.
引用
收藏
页码:252 / 253
页数:2
相关论文
共 2 条
[1]   Representational oligonucleotide microarray analysis: A high-resolution method to detect genome copy number variation [J].
Lucito, R ;
Healy, J ;
Alexander, J ;
Reiner, A ;
Esposito, D ;
Chi, MY ;
Rodgers, L ;
Brady, A ;
Sebat, J ;
Troge, J ;
West, JA ;
Rostan, S ;
Nguyen, KCQ ;
Powers, S ;
Ye, KQ ;
Olshen, A ;
Venkatraman, E ;
Norton, L ;
Wigler, M .
GENOME RESEARCH, 2003, 13 (10) :2291-2305
[2]   A common inversion under selection in Europeans [J].
Stefansson, H ;
Helgason, A ;
Thorleifsson, G ;
Steinthorsdottir, V ;
Masson, G ;
Barnard, J ;
Baker, A ;
Jonasdottir, A ;
Ingason, A ;
Gudnadottir, VG ;
Desnica, N ;
Hicks, A ;
Gylfason, A ;
Gudbjartsson, DF ;
Jonsdottir, GM ;
Sainz, J ;
Agnarsson, K ;
Birgisdottir, B ;
Ghosh, S ;
Olafsdottir, A ;
Cazier, JB ;
Kristjansson, K ;
Frigge, ML ;
Thorgeirsson, TE ;
Gulcher, JR ;
Kong, A ;
Stefansson, K .
NATURE GENETICS, 2005, 37 (02) :129-137