A mathematical model for elongation of a peptide chain

被引：16

作者：

Heyd, A ^{[1
]}

Drew, DA ^{[1
]}

机构：

[1] Rensselaer Polytech Inst, Dept Math Sci, Troy, NY 12180 USA

来源：

BULLETIN OF MATHEMATICAL BIOLOGY | 2003年 / 65卷 / 06期

关键词：

D O I：

10.1016/S0092-8240(03)00076-4

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A mathematical model is presented for the steps in the elongation process, and the steady-state elongation rate as a function of the amino acid concentrations is found. In addition, the reset sub-process of the elongation process is modeled. The rate of elongation of peptide chains is found to be a function of the concentration of the amino acid to be bound and the concentration of all other amino acids. In addition, the overall elongation rate depends on the concentrations of elongation factors. (C) 2003 Society for Mathematical Biology. Published by Elsevier Ltd. All rights reserved.

引用

页码：1095 / 1109

页数：15

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