Can stem cells cross lineage boundaries?

被引：369

作者：

Anderson, DJ ^{[1
]}

Gage, FH

Weissman, IL

机构：

[1] CALTECH, Howard Hughes Med Inst, Pasadena, CA 91125 USA

[2] Salk Inst Biol Studies, La Jolla, CA 92037 USA

[3] Stanford Univ, Stanford, CA 94305 USA

来源：

NATURE MEDICINE | 2001年 / 7卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/86439

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Stem cells have traditionally been characterized as either embryonic (pluripotent) or organ-specific. Recent work suggests that the latter can "transdifferentiate" into other cell types, carrying significant implications for possible clinical use of these cells. Here the authors critically examine the existing data, and suggest standards for the evaluation of these and future studies.

引用

页码：393 / 395

页数：3

共 20 条

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