Developments in matrix-assisted laser desorption ionization peptide mass spectrometry

被引：96

作者：

Mann, M

Talbo, G

机构：

[1] Protein and Peptides, EMBL, Heidelberg D-69117

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1996年 / 7卷 / 01期

关键词：

D O I：

10.1016/S0958-1669(96)80089-9

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Most characteristics of matrix-assisted laser desorption/ionization (MALDI) are ideal for the analysis of biomolecules. New preparation techniques have dramatically increased mass accuracy and resolution, making MALDI a high-performance mass spectrometric technique for peptide mass analysis. Attempts to obtain amino acid sequence information by MALDI have been partially successful. The technique has been put to novel uses in protein primary structure characterization.

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页码：11 / 19

页数：9

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