CGHMultiArray:: exact P-values for multi-array comparative genomic hybridization data

被引：36

作者：

van de Wiel, MA

Smeets, SJ

Brakenhoff, RH

Ylstra, B

机构：

[1] Tech Univ Edindhoven, Dept Math & Comp Sci, NL-5600 MB Eindhoven, Netherlands

[2] VU Univ, Med Ctr, Amsterdam, Netherlands

来源：

BIOINFORMATICS | 2005年 / 21卷 / 14期

关键词：

D O I：

10.1093/bioinformatics/bti489

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We compute P-values, based on the Wilcoxon test with ties, to compare two conditions with array comparative genomic hybridization data, and we provide a simple interface to export and plot these P-values.

引用

页码：3193 / 3194

页数：2

共 11 条

[1] Permutation distributions via generating functions with applications to sensitivity analysis of discrete data [J].

Baglivo, J ;

Pagano, M ;

Spino, C .

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1996, 91 (435) :1037-1046

[2] Efficient exact p-value computation for small sample, sparse, and surprising categorical data [J].

Bejerano, G ;

Friedman, N ;

Tishby, N .

JOURNAL OF COMPUTATIONAL BIOLOGY, 2004, 11 (05) :867-886

[3]

Benjamini Y, 2001, ANN STAT, V29, P1165

[4]

H?jek J., 1999, THEORY RANK TESTS

[5] Breakpoint identification and smoothing of array comparative genomic hybridization data [J].

Jong, K ;

Marchiori, E ;

Meijer, G ;

Van der Vaart, A ;

Ylstra, B .

BIOINFORMATICS, 2004, 20 (18) :3636-3637

[6] Circular binary segmentation for the analysis of array-based DNA copy number data [J].

Olshen, AB ;

Venkatraman, ES ;

Lucito, R ;

Wigler, M .

BIOSTATISTICS, 2004, 5 (04) :557-572

[7] Microarray-based comparative genomic hybridization and its applications in human genetics [J].

Oostlander, AE ;

Meijer, GA ;

Ylstra, B .

CLINICAL GENETICS, 2004, 66 (06) :488-495

[8]

Streitberg B, 1986, STATISTICAL SOFTWARE, V12, P10

[9] The split-up algorithm:: a fast symbolic method for computing p-values of distribution-free statistics [J].

van de Wiel, M .

COMPUTATIONAL STATISTICS, 2001, 16 (04) :519-538

[10] A method for calling gains and losses in array CGH data [J].

Wang, P ;

Kim, Y ;

Pollack, J ;

Narasimhan, B ;

Tibshirani, R .

BIOSTATISTICS, 2005, 6 (01) :45-58

← 1 2 →