The use of 1H NMR for yield determination in the regioselective epoxidation of squalene

被引：19

作者：

Aerts, HAJ ^{[1
]}

Sels, BFE ^{[1
]}

Jacobs, PA ^{[1
]}

机构：

[1] Katholieke Univ Leuven, Ctr Surface Chem & Catalysis, B-3001 Heverlee, Belgium

来源：

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY | 2005年 / 82卷 / 06期

关键词：

2,3-dpoxides; H-1; NMR; regioselective epoxidation; squalene;

D O I：

10.1007/s11746-005-1085-2

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

H-1 NMR can be used to determine the epoxide yield rapidly in the oxidation of squalene. Moreover, unequivocal distinction can be made between internal and terminal epoxide bonds. To underline the power of this technique, different stoichiometric and catalytic epoxidation procedures were carried out using squalene as substrate. They were characterized in terms of substrate conversion and regioselectivity of the epoxide fraction.

引用

页码：409 / 413

页数：5

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