Frequency of HLA-B alleles in a caucasoid population determined by a two-stage PCR-SSOP typing strategy

被引:37
作者
Middleton, D
Williams, F
Hamill, MA
Meenagh, A
机构
[1] City Hosp, No Ireland Reg Histocompatibil & Immunogenet Lab, Belfast BT9 7TS, Antrim, North Ireland
[2] Queens Univ Belfast, Belfast, Antrim, North Ireland
[3] Univ Ulster, Coleraine BT52 1SA, Londonderry, North Ireland
关键词
HLA-B allele frequency; SSOP;
D O I
10.1016/S0198-8859(00)00186-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
High resolution PCR-SSOP typing methods for HLA-B identification have been established and applied to a Northern Ireland population, using large enough numbers to give dependable allele frequencies. The six systems, which operate independently of each other, are intended for use as secondary typing systems following HLA-B identification with a medium resolution PCR-SSOP technique. (C) American Society for Histocompatibility and Immunogenetics, 2000. Published by Elsevier Science Inc.
引用
收藏
页码:1285 / 1297
页数:13
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