Macromollecullar recognition

被引：50

作者：

Deremble, C ^{[1
]}

Lavery, R ^{[1
]}

机构：

[1] Inst Biol Physicochim, CNRS, UPR 9080, Lab Biochim Theor, F-75005 Paris, France

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2005年 / 15卷 / 02期

关键词：

D O I：

10.1016/j.sbi.2005.01.018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Computational methods are being developed both to detect the binding surfaces of individual macromolecules and to predict the structure of binary macromolecular complexes. Speeding up and refining this process has required work on search algorithms, molecular representations and interaction potentials. Although backbone flexibility and solvent effects continue to pose problems, encouraging results have been obtained for both protein-protein and protein-DNA complexes.

引用

页码：171 / 175

页数：5

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