Synthesis and biological activities of novel seleno epi-daunomycin derivatives

被引：8

作者：

Zhang, SJ ^{[1
]}

Dong, JQ ^{[1
]}

Wang, YG ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 11期

关键词：

D O I：

10.1081/SCC-120020200

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3'-[2-(Selenoaryl)acetamido]epi-daunomycin derivatives 2a-d and 4'-[2-(selenoaryl)acetoxy]-N-(trifluoroacetyl)epi-daunomycin derivatives 4a-e were synthesized from epi-daunomycin 1d and N-trifluoroacetyl epi-daunomycin 3, respectively. These new compounds were assayed against human stomach cancer SGC-7901 and human leukaemia HL60.

引用

页码：1891 / 1898

页数：8

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