A comparison of the costs and effects of liver transplantation for acute and for chronic liver failure

被引：22

作者：

van Agthoven, M ^{[1
]}

Metselaar, HJ ^{[1
]}

Tilanus, HW ^{[1
]}

de Man, RA ^{[1
]}

IJzermans, JNM ^{[1
]}

van Ineveld, BM ^{[1
]}

机构：

[1] Erasmus Univ, Med Ctr, Dept Med Technol Assessment, NL-3000 DR Rotterdam, Netherlands

来源：

TRANSPLANT INTERNATIONAL | 2001年 / 14卷 / 02期

基金：

中国国家自然科学基金;

关键词：

liver transplantation; cost analysis; survival; acute liver failure; chronic liver failure;

D O I：

10.1007/s001470050852

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Little is known about costs and cost-effectiveness of liver transplantation (LTx) for acute liver failure compared to costs and cost-effectiveness of LTx for chronic liver failure. In this study, costs of acute and of chronic LTx patients were determined in a retrospective study. Files of 100 consecutive patients who underwent LTx in 1993-1997 were studied. Costs up to 1 year after LTx were Euro 107,675 (chronic liver failure) and Euro 90,792 (acute liver failure). The difference was mainly caused by higher hospitalisation costs and higher personnel costs for chronic liver failure. Medication costs for acute liver failure were higher, due to a high administration rate of expensive anti-HBs immunoglobulin therapy in patients with viral hepatitis B. LTx for chronic liver failure is more costly and seems to be more cost-effective than LTx for acute liver failure, since 1-year survival is higher in patients who underwent transplantation for chronic liver failure.

引用

页码：87 / 94

页数：8

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