Protein structure-based combinatorial chemistry: Discovery of non-peptide binding elements to Src SH3 domain

被引：79

作者：

Combs, AP ^{[1
]}

Kapoor, TM ^{[1
]}

Feng, SB ^{[1
]}

Chen, JK ^{[1
]}

DaudeSnow, LF ^{[1
]}

Schreiber, SL ^{[1
]}

机构：

[1] HARVARD UNIV, DEPT CHEM, HOWARD HUGHES MED INST, CAMBRIDGE, MA 02138 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 118卷 / 01期

关键词：

D O I：

10.1021/ja953750v

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：287 / 288

页数：2

共 12 条

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[3] BIASED COMBINATORIAL LIBRARIES - NOVEL LIGANDS FOR THE SH3 DOMAIN OF PHOSPHATIDYLINOSITOL 3-KINASE
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[4] 2 BINDING ORIENTATIONS FOR PEPTIDES TO THE SRC SH3 DOMAIN - DEVELOPMENT OF A GENERAL-MODEL FOR SH3-LIGAND INTERACTIONS
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[5] Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (26) : 12408 - 12415
[6] GENERAL-METHOD FOR RAPID SYNTHESIS OF MULTICOMPONENT PEPTIDE MIXTURES
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[7] A NEW TYPE OF SYNTHETIC PEPTIDE LIBRARY FOR IDENTIFYING LIGAND-BINDING ACTIVITY
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[J]. NATURE, 1991, 354 (6348) : 82 - 84
[8] Madden Dave, 1995, Perspectives in Drug Discovery and Design, V2, P269, DOI 10.1007/BF02172067
[9] COMPLEX SYNTHETIC CHEMICAL LIBRARIES INDEXED WITH MOLECULAR TAGS
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (23) : 10922 - 10926
[10] Pruschy M N, 1994, Chem Biol, V1, P163, DOI 10.1016/1074-5521(94)90006-X

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