The aromatic sidechains of amino acids as neutral donor groups for alkali metal cations

被引：79

作者：

Gokel, GW

机构：

[1] Washington Univ, Sch Med, Program Chem Biol, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Dept Mol Biol, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Dept Pharmacol, St Louis, MO 63110 USA

[4] Washington Univ, Sch Med, Dept Chem, St Louis, MO 63110 USA

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 23期

关键词：

D O I：

10.1039/b305483g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An aromatic residue that can serve as a pi- donor occurs in all known protein sequences about one out of every 11 amino acids. Benzene, phenol, and indole, the sidechains of phenylalanine, tyrosine, and tryptophan, are particularly important in protein structure. Solid state structures confirm the interactions of these neutral arenes, along with double and triple bonds, with sodium and potassium cations.

引用

页码：2847 / 2852

页数：6

共 43 条

[1]

ARNOLD KA, 1988, TETRAHEDRON LETT, P3025

[2] PI GROUPS IN ION-PAIR BONDING - STABILIZATION OF DIANION OF NAPHTHALENE BY LITHIUM TETRAMETHYLETHYLENEDIAMINE [J].