Highly enantioselective synthesis of multifunctionalized allylic building blocks via oxazaborolidine-catalyzed borane reduction

被引：11

作者：

Cho, BT ^{[1
]}

Shin, SH ^{[1
]}

机构：

[1] Hallym Univ, Dept Chem, Chunchon 200702, South Korea

来源：

TETRAHEDRON | 2005年 / 61卷 / 29期

关键词：

asymmetric reduction; oxazaborolidine-catalyzed reduction; chiral alkenyl beta-hydroxy sulfides; dianion alkylation; chiral alpha; beta-unsaturated diol;

D O I：

10.1016/j.tet.2005.05.018

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and convenient synthesis of optically active alkenyl beta-hydroxy sulfides with high enantiomeric excess by CBS-oxazaborolidine-catalyzed borane reduction of the corresponding beta-keto sulfides and its application to synthesis of chiral alkenic diols have been established. (c) 2005 Elsevier Ltd. All rights reserved.

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页码：6959 / 6966

页数：8

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