New aspects for the role of physical training in the management of patients with chronic heart failure

被引:29
作者
Adamopoulos, S [1 ]
Parissis, JT [1 ]
Kremastinos, DT [1 ]
机构
[1] Onassis Cardiac Surg Ctr, Dept Cardiovasc Med 2, Athens, Greece
关键词
physical training; endothelial dysfunction; skeletal muscle; inflammation; cytokines; chronic heart failure;
D O I
10.1016/S0167-5273(02)00504-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recent experimental and clinical data have shown that physical training is an important therapeutic intervention in the management of patients with chronic heart failure (CHF), improving central hemodynamics and attenuating peripheral abnormalities (endothelial dysfunction and skeletal myopathy) characterizing the progression of the syndrome. Additionally, physical training seems to beneficially modulate peripheral immune responses of CHF expressed by elevated circulating proinflammatory cytokines, soluble cellular adhesion molecules and soluble apoptosis signaling molecules, resulting in improvement in exercise capacity of CHF patients. This article summarizes current knowledge about the beneficial role of physical training in CHF, as well as about traditional and novel mechanisms contributing to the physical training-induced improvement in clinical performance of CHF patients. (C) 2002 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:1 / 14
页数:14
相关论文
共 120 条
[1]   PHYSICAL-TRAINING IMPROVES SKELETAL-MUSCLE METABOLISM IN PATIENTS WITH CHRONIC HEART-FAILURE [J].
ADAMOPOULOS, S ;
COATS, AJS ;
BRUNOTTE, F ;
ARNOLDA, L ;
MEYER, T ;
THOMPSON, CH ;
DUNN, JF ;
STRATTON, J ;
KEMP, GJ ;
RADDA, GK ;
RAJAGOPALAN, B .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1993, 21 (05) :1101-1106
[2]   Physical training modulates proinflammatory cytokines and the soluble Fas/soluble Fas ligand system in patients with chronic heart failure [J].
Adamopoulos, S ;
Parissis, J ;
Karatzas, D ;
Kroupis, C ;
Georgiadis, M ;
Karavolias, G ;
Paraskevaidis, J ;
Koniavitou, K ;
Coats, AJS ;
Kremastinos, DT .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 39 (04) :653-663
[3]  
Adamopoulos S, 2001, CIRCULATION, V104, P608
[4]  
Adamopoulos S, 2000, CIRCULATION, V102, P522
[5]   Physical training reduces peripheral markers of inflammation in patients with chronic heart failure [J].
Adamopoulos, S ;
Parissis, J ;
Kroupis, C ;
Georgiadis, M ;
Karatzas, D ;
Karavolias, G ;
Koniavitou, K ;
Coats, AJS ;
Kremastinos, DT .
EUROPEAN HEART JOURNAL, 2001, 22 (09) :791-797
[6]   A glossary of circulating cytokines in chronic heart failure [J].
Adamopoulos, S ;
Parissis, JT ;
Kremastinos, DT .
EUROPEAN JOURNAL OF HEART FAILURE, 2001, 3 (05) :517-526
[7]   CIRCADIAN PATTERN OF HEART-RATE-VARIABILITY IN CHRONIC HEART-FAILURE PATIENTS - EFFECTS OF PHYSICAL-TRAINING [J].
ADAMOPOULOS, S ;
PONIKOWSKI, P ;
CERQUETANI, E ;
PIEPOLI, M ;
ROSANO, G ;
SLEIGHT, P ;
COATS, AJS .
EUROPEAN HEART JOURNAL, 1995, 16 (10) :1380-1386
[8]   Elevated circulating levels of C-C chemokines in patients with congestive heart failure [J].
Aukrust, P ;
Ueland, T ;
Müller, F ;
Andreassen, AK ;
Nordoy, I ;
Aas, H ;
Kjekshus, J ;
Simonsen, S ;
Froland, SS ;
Gullestad, L .
CIRCULATION, 1998, 97 (12) :1136-1143
[9]   Randomized, controlled trial of long-term moderate exercise training in chronic heart failure - Effects on functional capacity, quality of life, and clinical outcome [J].
Belardinelli, R ;
Georgiou, D ;
Cianci, G ;
Purcaro, A .
CIRCULATION, 1999, 99 (09) :1173-1182
[10]   LOW-INTENSITY EXERCISE TRAINING IN PATIENTS WITH CHRONIC HEART-FAILURE [J].
BELARDINELLI, R ;
GEORGIOU, D ;
SCOCCO, V ;
BARSTOW, TJ ;
PURCARO, A .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1995, 26 (04) :975-982