Inhaled nitric oxide improves exercise capacity in patients with severe heart failure and right ventricular dysfunction

被引：24

作者：

Koelling, TM

Kirmse, M

Di Salvo, TG

Dec, GW

Zapol, WM

Semigran, MJ

机构：

[1] Massachusetts Gen Hosp, Heart Failure & Cardiac Transplantat Ctr, Cardiac Unit, Dept Med, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Anesthesia & Crit Care, Boston, MA 02114 USA

[3] Harvard Univ, Sch Med, Boston, MA USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1998年 / 81卷 / 12期

关键词：

D O I：

10.1016/S0002-9149(98)00214-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Fourteen cardiac transplant candidates were studied with cardiopulmonary exercise testing at baseline and while breathing nitric oxide (40 ppm). Oxygen consumption at the anaerobic threshold was improved by breathing nitric oxide in patients with pulmonary hypertension and in patients with an elevated left ventricular end-diastolic volume index.

引用

页码：1494 / +

页数：5

共 10 条

[1] A NEW METHOD FOR DETECTING ANAEROBIC THRESHOLD BY GAS-EXCHANGE [J].

BEAVER, WL ;

WASSERMAN, K ;

WHIPP, BJ .

JOURNAL OF APPLIED PHYSIOLOGY, 1986, 60 (06) :2020-2027

[2] INHALED NITRIC-OXIDE LEADING TO PULMONARY-EDEMA IN STABLE SEVERE HEART-FAILURE [J].

BOCCHI, EA ;

BACAL, F ;

AULER, JOC ;

CARMONE, MJD ;

BELLOTTI, G ;

PILEGGI, F .

AMERICAN JOURNAL OF CARDIOLOGY, 1994, 74 (01) :70-72

[3] EFFECT OF VASODILATOR THERAPY ON MORTALITY IN CHRONIC CONGESTIVE-HEART-FAILURE - RESULTS OF A VETERANS-ADMINISTRATION COOPERATIVE STUDY [J].

COHN, JN ;

ARCHIBALD, DG ;

ZIESCHE, S ;

FRANCIOSA, JA ;

HARSTON, WE ;

TRISTANI, FE ;

DUNKMAN, WB ;

JACOBS, W ;

FRANCIS, GS ;

FLOHR, KH ;

GOLDMAN, S ;

COBB, FR ;

SHAH, PM ;

SAUNDERS, R ;

FLETCHER, RD ;

LOEB, HS ;

HUGHES, VC ;

BAKER, B .

NEW ENGLAND JOURNAL OF MEDICINE, 1986, 314 (24) :1547-1552

[4]

COHN JN, 1993, CIRCULATION S, V87, P15

[5] INFLUENCE OF PREOPERATIVE PULMONARY-ARTERY PRESSURE ON MORTALITY AFTER HEART-TRANSPLANTATION - TESTING OF POTENTIAL REVERSIBILITY OF PULMONARY-HYPERTENSION WITH NITROPRUSSIDE IS USEFUL IN DEFINING A HIGH-RISK GROUP [J].

COSTARDJACKLE, A ;

FOWLER, MB .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1992, 19 (01) :48-54

[6]

Dickstein ML, 1996, J HEART LUNG TRANSPL, V15, P715

[7] PRESERVED RIGHT-VENTRICULAR EJECTION FRACTION PREDICTS EXERCISE CAPACITY AND SURVIVAL IN ADVANCED HEART-FAILURE [J].

DISALVO, TG ;

MATHIER, M ;

SEMIGRAN, MJ ;

DEC, GW .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1995, 25 (05) :1143-1153

[8] IMPROVED EXERCISE CAPACITY AND DIFFERING ARTERIAL AND VENOUS TOLERANCE DURING CHRONIC ISOSORBIDE DINITRATE THERAPY FOR CONGESTIVE HEART-FAILURE [J].

LEIER, CV ;

HUSS, P ;

MAGORIEN, RD ;

UNVERFERTH, DV .

CIRCULATION, 1983, 67 (04) :817-822

[9] CARDIOVASCULAR EFFECTS OF INHALED NITRIC-OXIDE IN PATIENTS WITH LEFT-VENTRICULAR DYSFUNCTION [J].

LOH, E ;

STAMLER, JS ;

HARE, JM ;

LOSCALZO, J ;

COLUCCI, WS .

CIRCULATION, 1994, 90 (06) :2780-2785

[10] HEMODYNAMIC-EFFECTS OF INHALED NITRIC-OXIDE IN HEART-FAILURE [J].

SEMIGRAN, MJ ;

COCKRILL, BA ;

KACMAREK, R ;

THOMPSON, BT ;

ZAPOL, WM ;

DEC, GW ;

FIFER, MA .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1994, 24 (04) :982-988

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