Identification of a 25-kilodalton protein of Mycobacterium bovis BCG to distinguish BCG strains from Mycobacterium tuberculosis

被引：2

作者：

Kumar, D ^{[1
]}

Srivastava, BS ^{[1
]}

Singh, NB ^{[1
]}

Srivastava, R ^{[1
]}

机构：

[1] CENT DRUG RES INST,DIV MICROBIAL GENET,LUCKNOW 226001,UTTAR PRADESH,INDIA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1996年 / 34卷 / 01期

关键词：

D O I：

10.1128/JCM.34.1.224-226.1996

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Mycobacterium bovis BCG vaccine strains were compared with A Mycobacterium tuberculosis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, A 25-kDa protein observed in the BCG strains was absent in M. tuberculosis. Rabbit antibodies specific to the 25-kDa protein uniquely identified this protein in BCG strains but not in M. tuberculosis. It is suggested that the 25-kDa protein acid polyclonal antibodies directed against this antigen can be exploited to distinguish BCG strains from M. tuberculosis.

引用

页码：224 / 226

页数：3

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