Aberrant cytoplasmic expression of C-terminal-truncated NPM leukaemic mutant is dictated by tryptophans loss and a new NES motif

被引：25

作者：

Falini, B. ^{[1
]}

Albiero, E.

Bolli, N.

De Marco, M. F.

Madeo, D.

Martelli, M.

Nicoletti, I.

Rodeghiero, F.

机构：

[1] Univ Perugia, Inst Haematol, I-06100 Perugia, Italy

[2] San Bortolo Hosp, Dept Cell Therapy, Vicenza, Italy

[3] Univ Perugia, Inst Internal Med, I-06100 Perugia, Italy

来源：

LEUKEMIA | 2007年 / 21卷 / 09期

关键词：

D O I：

10.1038/sj.leu.2404839

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：2052 / 2054

页数：4

共 6 条

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[5] Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML [J].

Falini, Brunangelo ;

Bolli, Niccolò ;

Shan, Jing ;

Martelli, Maria Paola ;

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Pasqualucci, Laura ;

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