Interest of the ketogenic:: diet in a refractory status epilepticus in adults

被引:58
作者
Bodenant, M. [1 ]
Moreau, C. [1 ]
Sejourne, C. [2 ]
Auvin, S. [3 ]
Delval, A. [4 ]
Cuisset, J. -M.
Derambure, P. [4 ]
Destee, A. [1 ]
Defebvre, L. [1 ]
机构
[1] CHRU, Hop Roger Salengro, Neurol Clin, Serv Neurol & Pathol Mouvement,EA 2683,IFR 114, F-59037 Lille, France
[2] CHRU, Hop Roger Salengro, Serv Reanimat Polyvalente, F-59037 Lille, France
[3] CHRU, Hop Roger Salengro, Serv Neuropediat, F-59037 Lille, France
[4] CHRU, Hop Roger Salengro, Serv Neurophysiol, EA 2683, F-59037 Lille, France
关键词
ketogenic diet; refractory status epilepticus; therapy;
D O I
10.1016/j.neurol.2007.08.009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction. - Ketogenic diets have been employed for the treatment of intractable epilepsiy in children since 1921, although underlying mechanism remains unknown. Observation. - We report the case of a 54-year-old man with partial refractory status epilepticus who exhibited a favourable outcome about seven days after introduction of a ketogenic diet in association with antiepileptic drugs. Discussion. - Although its efficiency was largely demonstrated in children, little is known about the impact of a ketogenic diet in adults with refractory epilepsy. Conclusion. - Introduction of a ketogenic diet requires a multidisciplinary approach. Its usefulness in adult intractable epilepsy and/or refractory status epilepticus merits further study into its efficacy in reducing the frequency of seizures and a possible prolonged effect. (c) 2007 Elsevier Masson SAS. Tous droits reserves.
引用
收藏
页码:194 / 199
页数:6
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