Vicarious nucleophilic substitution of hydrogen and formation of aziridine rings in reactions of benzonaphthyridines and their N-oxides with chloromethyl phenyl sulfone

被引：13

作者：

Bachowska, B ^{[1
]}

Zujewska, T ^{[1
]}

机构：

[1] Pedag Univ Czestochowa, Inst Chem, PL-42201 Czestochowa, Poland

来源：

MONATSHEFTE FUR CHEMIE | 2001年 / 132卷 / 07期

关键词：

benzonaphthyridine N-oxides; vicarious nucleophilic substitution (VNS); annulation; alpha-halo carbanions;

D O I：

10.1007/s007060170073

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Treatment of benzonaphthyridines with chloromethyl phenyl sulfone in the presence of base led to the formation of aziridine rings annelated to the benzonaphthyridine skeleton, whereas their N-oxides underwent vicarious nucleophilic substitution of hydrogen (VNS), thus leading to the corresponding phenylsulfonylmethyl derivatives.

引用

页码：849 / 854

页数：6

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