pH, EF-1 alpha and the cytoskeleton

被引:44
作者
Liu, G
Edmonds, BT
Condeelis, J
机构
关键词
D O I
10.1016/0962-8924(96)20013-3
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
One of the unexpected cellular components found interacting with the cytoskeleton is elongation factor 1 alpha (EF-1 alpha). How this interaction is regulated is not clear, but pH may be a potent regulator. Interestingly, pH also regulates the amount of protein translation occurring in many cell systems. In this paper, the authors suggest that sequestration of EF-1 alpha in the cytoskeleton may play a key role in regulating the spatial distribution of macromolecular assembly in a way that is dependent on cytoplasmic pH.
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页码:168 / 171
页数:4
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