Inherited defects in the DNA glycosylase MYH cause multiple colorectal adenoma and carcinoma

被引：16

作者：

Cheadle, JP ^{[1
]}

Dolwani, S ^{[1
]}

Sampson, JR ^{[1
]}

机构：

[1] Univ Wales Coll Med, Inst Med Genet, Cardiff CF14 4XN, S Glam, Wales

来源：

CARCINOGENESIS | 2003年 / 24卷 / 07期

关键词：

D O I：

10.1093/carcin/bgg068

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1281 / 1282

页数：2

共 15 条

[1] Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors [J].

Al-Tassan, N ;

Chmiel, NH ;

Maynard, J ;

Fleming, N ;

Livingston, AL ;

Williams, GT ;

Hodges, AK ;

Davies, DR ;

David, SS ;

Sampson, JR ;

Cheadle, JR .

NATURE GENETICS, 2002, 30 (02) :227-232

[2] ENDOGENOUS MUTAGENS AND THE CAUSES OF AGING AND CANCER [J].

AMES, BN ;

GOLD, LS .

MUTATION RESEARCH, 1991, 250 (1-2) :3-16

[3] hMYH cell cycle-dependent expression, subcellular localization and association with replication foci:: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs [J].

Boldogh, I ;

Milligan, D ;

Lee, MS ;

Bassett, H ;

Lloyd, RS ;

McCullough, AK .

NUCLEIC ACIDS RESEARCH, 2001, 29 (13) :2802-2809

[4] The discovery of a new family of mammalian enzymes for repair of oxidatively damaged DNA, and its physiological implications [J].

Hazra, TK ;

Izumi, T ;

Kow, YW ;

Mitra, S .

CARCINOGENESIS, 2003, 24 (02) :155-157

[5] Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C→T:A mutations [J].

Jones, S ;

Emmerson, P ;

Maynard, J ;

Best, JM ;

Jordan, S ;

Williams, GT ;

Sampson, JR ;

Cheadle, JP .

HUMAN MOLECULAR GENETICS, 2002, 11 (23) :2961-2967

[6] THE GO SYSTEM PROTECTS ORGANISMS FROM THE MUTAGENIC EFFECT OF THE SPONTANEOUS LESION 8-HYDROXYGUANINE (7,8-DIHYDRO-8-OXOGUANINE) [J].

MICHAELS, ML ;

MILLER, JH .

JOURNAL OF BACTERIOLOGY, 1992, 174 (20) :6321-6325

[7] MUTATIONS IN THE MUTY GENE OF ESCHERICHIA-COLI ENHANCE THE FREQUENCY OF TARGETED G-C-]T-A TRANSVERSIONS INDUCED BY A SINGLE 8-OXOGUANINE RESIDUE IN SINGLE-STRANDED-DNA [J].

MORIYA, M ;

GROLLMAN, AP .

MOLECULAR & GENERAL GENETICS, 1993, 239 (1-2) :72-76

[8] THE MUTY GENE - A MUTATOR LOCUS IN ESCHERICHIA-COLI THAT GENERATES G.C-]T.A TRANSVERSIONS [J].

NGHIEM, Y ;

CABRERA, M ;

CUPPLES, CG ;

MILLER, JH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (08) :2709-2713

[9] Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair [J].

Parker, A ;

Gu, YS ;

Mahoney, W ;

Lee, SH ;

Singh, KK ;

Lu, AL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (08) :5547-5555

[10] Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase [J].

RoldanArjona, T ;

Wei, YF ;

Carter, KC ;

Klungland, A ;

Anselmino, C ;

Wang, RP ;

Augustus, M ;

Lindahl, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (15) :8016-8020

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