Protracted benefit from paradoxical kinesia in typical and atypical parkinsonisms

被引:20
作者
Bonanni, L. [1 ,2 ]
Thomas, A. [1 ,2 ]
Anzellotti, F. [1 ,2 ]
Monaco, D. [1 ,2 ]
Ciccocioppo, F. [1 ,2 ]
Varanese, S. [1 ,2 ]
Bifolchetti, S. [1 ,2 ]
D'Amico, M. C. [1 ,2 ]
Di Iorio, A. [3 ]
Onofrj, M. [1 ,2 ]
机构
[1] Gabriele dAnnunzio Univ Fdn, CeSI, Aging Res Ctr, Dept Neurosci & Imaging, I-66013 Chieti, Italy
[2] Univ G DAnnunzio, Dept Neurosci & Imaging, Chieti, Italy
[3] Univ G DAnnunzio, Dept Med & Aging, Geriatr Unit, Lab Clin Epidemiol, Chieti, Italy
关键词
Paradoxical kinesia; Parkinson's disease; Freezing of gait; LEWY BODIES; DISEASE; DIAGNOSIS; DEMENTIA;
D O I
10.1007/s10072-010-0403-5
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Paradoxical kinesia (PK) is the sudden resolution of a previously stabilized akinesia in an advanced idiopathic Parkinson's disease (IPD) patient facing an immediate threat. We are reporting the effect of PK, as a consequence of a life threatening event (earthquake), in a group of 14 patients with parkinsonism and dementia in Hoehn/Yahr (H/Y) stage 3-5. All the patients presented an extraordinary motor response during the earthquake that has recently stricken the Italian city of L'Aquila. All of them were able to safely escape unaided and, in some cases, to assist their families, despite they suffered before from severe night time akinesia and gait difficulties with postural instability requiring assistance. In five patients, the improvement of motor disabilities, particularly of freezing, lasted for 2-5 months.
引用
收藏
页码:751 / 756
页数:6
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