Synthesis of 5,6-difluoroarachidonic acid, a potential inhibitor of 5-lipoxygenase

被引:9
作者
Bildstein, S [1 ]
Ducep, JB [1 ]
Jacobi, D [1 ]
Zimmermann, P [1 ]
机构
[1] MARION MERRELL RES INST,STRASBOURG RES CTR,F-67080 STRASBOURG,FRANCE
关键词
D O I
10.1016/0040-4039(96)00976-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of 5,6-difluoroarachidonic acid 1 is described. The vicinal difluorinated double bond was prepared from the alpha-phenylthio-beta-ketoester 4. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:4941 / 4944
页数:4
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