Granulomatous Amebic Encephalitis in a Child with Acute Lymphoblastic Leukemia Successfully Treated with Multimodal Antimicrobial Therapy and Hyperbaric Oxygen

被引：29

作者：

Maritschnegg, P. ^{[1
]}

Sovinz, P. ^{[1
]}

Lackner, H. ^{[1
]}

Benesch, M. ^{[1
]}

Nebl, A. ^{[1
]}

Schwinger, W. ^{[1
]}

Walochnik, J. ^{[2
]}

Urban, C. ^{[1
]}

机构：

[1] Med Univ Graz, Dept Pediat & Adolescent Med, Div Pediat Hematol Oncol, A-8036 Graz, Austria

[2] Med Univ Vienna, Inst Specif Prophylaxis & Trop Med, Dept Med Parasitol, Vienna, Austria

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 01期

关键词：

ACANTHAMOEBA INFECTION; ABSCESS; DISEASE;

D O I：

10.1128/JCM.01456-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

Acanthamoeba is the causative agent of granulomatous amebic encephalitis, a rare and usually fatal disease. We report a child with acute lymphoblastic leukemia who developed brain abscesses caused by Acanthamoeba during induction therapy. Multimodal antimicrobial chemotherapy and hyperbaric oxygen therapy resulted in complete resolution of symptoms and of pathology as seen by magnetic resonance imaging.

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收藏

页码：446 / 448

页数：3

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