Oxysterols found in opacified cornea of fish

被引：5

作者：

Adachi, J ^{[1
]}

Hojo, K ^{[1
]}

Naito, T ^{[1
]}

Tatsuno, Y ^{[1
]}

机构：

[1] KOBE PHARMACEUT UNIV,KOBE,HYOGO 658,JAPAN

来源：

LIPIDS | 1996年 / 31卷 / 10期

关键词：

D O I：

10.1007/BF02522460

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We describe a new concept implicating oxidized cholesterol derivatives and very long-chain fatty acids as possible factors in the development of corneal opacification after death. Corneal tissues, removed from both fresh and stale fish eyes, were examined for cholesterol derivatives and fatty acids after methanolysis of lipids. Cholesta-3,5-dien-7-one, cholest-4-en-3-one, hexacosanoic acid, and hexacosenoic acid were identified via gas chromatography/mass spectrometry in opacified corneas, but not in significant amounts in fresh ones. The present study confirmed the presence of lipid hydrolysis and a peroxidation process in the opacified cornea.

引用

页码：1039 / 1043

页数：5

共 19 条

[1]

ACKMAN RG, 1987, ACTA MED SCAND, V222, P99

[2] Identification of cholesta-3,5-dien-7-one by gas chromatography mass spectrometry in the erythrocyte membrane of alcoholic patients [J].