共 3 条
- [1] 2008, NAT REV DRUG DISCOV, V7, P717
- [2] 2009, ANN NEUROL, V66, P48
- [3] 2010, NAT REV DRUG DISCOV, V9, P579
Alzheimer's failure raises questions about disease-modifying strategies
被引：131
作者：
Extance, Andy
机构：
关键词：
D O I：
10.1038/nrd3288
中图分类号：
Q81 [生物工程学（生物技术）];
Q93 [微生物学];
学科分类号：
071005 ;
0836 ;
090102 ;
100705 ;
摘要：
Do the lack of efficacy and the increase in the risk of skin cancer seen in Phase III trials of Eli Lilly's γ-secretase inhibitor undermine the potential of targeting this enzyme for the treatment of Alzheimer's disease?
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页码：749 / U87
页数：3
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