β-blocker use, BMD, and fractures in the study of osteoporotic fractures

被引：116

作者：

Reid, IR

Gamble, GD

Grey, AB

Black, DM

Ensrud, KE

Browner, WS

Bauer, DC

机构：

[1] Univ Auckland, Dept Med, Auckland 1, New Zealand

[2] Univ Calif San Francisco, Div Gen Internal Med, Dept Med, San Francisco, CA 94143 USA

[3] Minneapolis Vet Affairs Med Ctr, Dept Med, Minneapolis, MN USA

[4] Minneapolis Vet Affairs Med Ctr, Dept Epidemiol, Minneapolis, MN USA

[5] Univ Minnesota, Minneapolis, MN USA

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2005年 / 20卷 / 04期

关键词：

osteoporosis; central nervous system; leptin;

D O I：

10.1359/JBMR.041202

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

A role for osteoblastic beta-adrenoreceptors in bone regulation is suggested by the finding that beta-blockers increase bone mass in mice. We studied the association of R-blocker use with BMD and fractures in the Study of Osteoporotic Fractures. P-blocker use and BMD are unrelated in this cohort, and associations with fracture risk are inconsistent.

引用

收藏

页码：613 / 618

页数：6

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