A highly stereocontrolled formal synthesis of rac-chokols A and G from a common gem-borazirconocene intermediate

被引:14
作者
Deloux, L [1 ]
Srebnik, M [1 ]
机构
[1] UNIV TOLEDO,DEPT CHEM,TOLEDO,OH 43606
关键词
D O I
10.1016/0040-4039(96)00389-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The stereoselective synthesis of rac-chokols A and G precursors described herein proceeds from the readily available gem-borazirconocene 2 by conjugate addition to 2-methylcyclopentenone to give the common intermediate 3, which is then transformed in a series of reactions to provide the chokols in overall yields of 16 and 17% respectively. Copyright (C) 1996 Elsevier Science Ltd.
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页码:2735 / 2738
页数:4
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