Fast computation of minimum hybridization networks

被引:39
作者
Albrecht, Benjamin [1 ]
Scornavacca, Celine [1 ]
Cenci, Alberto [2 ]
Huson, Daniel H. [1 ]
机构
[1] Univ Tubingen, Dept Comp Sci, Ctr Bioinformat ZBIT, D-72076 Tubingen, Germany
[2] IRD, F-34394 Montpellier 5, France
关键词
CONSISTENT EVOLUTIONARY HISTORY; HYBRID SPECIATION; AGREEMENT FORESTS; NUMBER; ALGORITHMS; PHYLOGENY; EVENTS; TREES; TIME; FPT;
D O I
10.1093/bioinformatics/btr618
中图分类号
Q5 [生物化学];
学科分类号
070307 [化学生物学];
摘要
Results: We describe how to compute a representative set of minimum hybridization networks for two given bifurcating input trees, using a parallel algorithm and provide a user-friendly implementation. A simulation study suggests that our program performs significantly better than existing software on biologically relevant data. Finally, we demonstrate the application of such methods in the context of the evolution of the Aegilops/Triticum genera.
引用
收藏
页码:191 / 197
页数:7
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