Spectrofluorometric determination of ibuprofen in pharmaceutical formulations

被引：53

作者：

Damiani, PC ^{[1
]}

Bearzotti, M ^{[1
]}

Cabezón, MA ^{[1
]}

机构：

[1] Univ Nacl Rosario, Fac Ciencias Bioquim & Farmaceut, Dept Quim Analit, RA-2000 Rosario, Santa Fe, Argentina

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2001年 / 25卷 / 3-4期

关键词：

spectrofluorometry; determination of ibuprofen; ibuprofen;

D O I：

10.1016/S0731-7085(00)00584-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The spectrofluorometric determination of ibuprofen in pharmaceutical tablets, creams and syrup is described. It involves excitation at 263 nm and emission at 288 nm. The linear range is 2-73 mg L-1. Other drugs or excipients present in the different formulations do not interfere, except in the case of chlorzoxazone containing tablets. Due to its strong absorbance in the spectral range the chlorzoxazone does interfere, so that in this case the proposed method can't be applied. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：679 / 683

页数：5

共 40 条

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