Human nutrition, the gut microbiome and the immune system

被引：1928

作者：

Kau, Andrew L. ^{[1
]}

Ahern, Philip P. ^{[1
]}

Griffin, Nicholas W. ^{[1
]}

Goodman, Andrew L. ^{[1
]}

Gordon, Jeffrey I. ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Ctr Genome Sci & Syst Biol, St Louis, MO 63108 USA

来源：

NATURE | 2011年 / 474卷 / 7351期

基金：

美国国家卫生研究院;

关键词：

ARYL-HYDROCARBON RECEPTOR; T-CELLS; SMALL-BOWEL; INTESTINAL MICROFLORA; CHILD UNDERNUTRITION; INSULIN-RESISTANCE; INNATE IMMUNITY; ADIPOSE-TISSUE; KEY ROLE; OBESITY;

D O I：

10.1038/nature10213

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Marked changes in socio-economic status, cultural traditions, population growth and agriculture are affecting diets worldwide. Understanding how our diet and nutritional status influence the composition and dynamic operations of our gut microbial communities, and the innate and adaptive arms of our immune system, represents an area of scientific need, opportunity and challenge. The insights gleaned should help to address several pressing global health problems.

引用

页码：327 / 336

页数：10

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