A model of a snorer's upper airway

被引:36
作者
Aittokallio, T [1 ]
Gyllenberg, M
Polo, O
机构
[1] Univ Turku, Dept Math, Turku 20014, Finland
[2] Turku Ctr Comp Sci TUCS, Washington, DC 20520 USA
[3] Univ Turku, Dept Physiol, FIN-20520 Turku, Finland
基金
芬兰科学院;
关键词
flow in collapsible tube; flow limitation; partial upper airway obstruction; sleep apnea; snoring; upper airway muscles;
D O I
10.1016/S0025-5564(00)00062-6
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In snorers, the physiologic decrease of postural muscle tone during sleep results in increased collapsibility of the upper airway. Measurement of nasal pressure changes with prongs is increasingly used to monitor flow kinetics through a collapsing upper airway. This report presents a mathematical model to predict nasal flow profile from three critical components that control upper airway patency during sleep. The model includes the respiratory pump drive, the stiffness of the pharyngeal soft tissues, and the dynamic support of the muscles surrounding the upper airway. Depending on these three components, the proposed model is able to reproduce the characteristic changes in flow profile that are clinically observed in snorers and nonsnorers during sleep. (C) 2001 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:79 / 90
页数:12
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