Asymmetric sulfur ylide mediated aziridination: Application in the synthesis of the side chain of taxol

被引：102

作者：

Aggarwal, VK ^{[1
]}

Vasse, JL ^{[1
]}

机构：

[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 21期

关键词：

D O I：

10.1021/ol035554w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sulfur ylide methodology has been used to construct the Taxol side chain with a high degree of enantioselectivity via a trans-aziridine followed by stereospecific rearrangement of the trans-benzoylaziridine into a trans-oxazoline.

引用

页码：3987 / 3990

页数：4

共 36 条

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