Efg1, a morphogenetic regulator in Candida albicans, is a sequence-specific DNA binding protein

被引:60
作者
Leng, P [1 ]
Lee, PR [1 ]
Wu, H [1 ]
Brown, AJP [1 ]
机构
[1] Univ Aberdeen, Inst Med Sci, Dept Mol & Cell Biol, Aberdeen AB25 2ZD, Scotland
基金
英国惠康基金;
关键词
D O I
10.1128/JB.183.13.4090-4093.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Efg1 is essential for hyphal development in the human pathogen Candida albicans under most conditions. Efg1 is related to basic helix-loop-helix regulators, and therefore most workers presume that Efg1 is a transcription factor. Here we confirm that Efg1 is a DNA binding protein that can interact specifically with the E box.
引用
收藏
页码:4090 / 4093
页数:4
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