Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms

被引：182

作者：

Abdel-Wahab, O. ^{[1
,2
]}

Pardanani, A. ^{[3
]}

Patel, J. ^{[1
]}

Wadleigh, M. ^{[4
]}

Lasho, T. ^{[3
]}

Heguy, A. ^{[1
]}

Beran, M. ^{[5
]}

Gilliland, D. G. ^{[6
]}

Levine, R. L. ^{[1
,2
]}

Tefferi, A. ^{[3
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Human Oncol & Pathogenesis Program, New York, NY 10021 USA

[2] Mem Sloan Kettering Canc Ctr, Leukemia Serv, Dept Med, New York, NY 10021 USA

[3] Mayo Clin, Div Hematol, Rochester, MN USA

[4] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA

[5] MD Anderson Canc, Div Leukemia, Houston, TX 77030 USA

[6] Merck & Co Inc, N Wales, PA USA

来源：

LEUKEMIA | 2011年 / 25卷 / 07期

关键词：

MYELOID-LEUKEMIA; GENE; PROGRESSION; TET2;

D O I：

10.1038/leu.2011.58

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：1200 / 1202

页数：3

共 8 条

[1] High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression [J].

Boultwood, J. ;

Perry, J. ;

Zaman, R. ;

Fernandez-Santamaria, C. ;

Littlewood, T. ;

Kusec, R. ;

Pellagatti, A. ;

Wang, L. ;

Clark, R. E. ;

Wainscoat, J. S. .

LEUKEMIA, 2010, 24 (06) :1139-1145

[2] Mutual exclusion of ASXL1 and NPM1 mutations in a series of acute myeloid leukemias [J].

Carbuccia, N. ;

Trouplin, V. ;

Gelsi-Boyer, V. ;

Murati, A. ;

Rocquain, J. ;

Adelaide, J. ;

Olschwang, S. ;

Xerri, L. ;

Vey, N. ;

Chaffanet, M. ;

Birnbaum, D. ;

Mozziconacci, M. J. .

LEUKEMIA, 2010, 24 (02) :469-473

[3] Mutations of ASXL1 gene in myeloproliferative neoplasms [J].

Carbuccia, N. ;

Murati, A. ;

Trouplin, V. ;

Brecqueville, M. ;

Adelaide, J. ;

Rey, J. ;

Vainchenker, W. ;

Bernard, O. A. ;

Chaffanet, M. ;

Vey, N. ;

Birnbaum, D. ;

Mozziconacci, M. J. .

LEUKEMIA, 2009, 23 (11) :2183-2186

[4] Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders [J].

Ernst, Thomas ;

Chase, Andrew J. ;

Score, Joannah ;

Hidalgo-Curtis, Claire E. ;

Bryant, Catherine ;

Jones, Amy V. ;

Waghorn, Katherine ;

Zoi, Katerina ;

Ross, Fiona M. ;

Reiter, Andreas ;

Hochhaus, Andreas ;

Drexler, Hans G. ;

Duncombe, Andrew ;

Cervantes, Francisco ;

Oscier, David ;

Boultwood, Jacqueline ;

Grand, Francis H. ;

Cross, Nicholas C. P. .

NATURE GENETICS, 2010, 42 (08) :722-U109

[5] ASXL1 mutation is associated with poor prognosis and acute transformation in chronic myelomonocytic leukaemia [J].

Gelsi-Boyer, Veronique ;

Trouplin, Virginie ;

Roquain, Julien ;

Adelaide, Jose ;

Carbuccia, Nadine ;

Esterni, Benjamin ;

Finetti, Pascal ;

Murati, Anne ;

Arnoulet, Christine ;

Zerazhi, Hacene ;

Fezoui, Hacene ;

Tadrist, Zoulika ;

Nezri, Meyer ;

Chaffanet, Max ;

Mozziconacci, Marie-Joeelle ;

Vey, Norbert ;

Birnbaum, Daniel .

BRITISH JOURNAL OF HAEMATOLOGY, 2010, 151 (04) :365-375

[6] Dynamic International Prognostic Scoring System (DIPSS) predicts progression to acute myeloid leukemia in primary myelofibrosis [J].

Passamonti, Francesco ;

Cervantes, Francisco ;

Vannucchi, Alessandro Maria ;

Morra, Enrica ;

Rumi, Elisa ;

Cazzola, Mario ;

Tefferi, Ayalew .

BLOOD, 2010, 116 (15) :2857-2858

[7] Genetic typing of CBL, ASXL1, RUNX1, TET2 and JAK2 in juvenile myelomonocytic leukaemia reveals a genetic profile distinct from chronic myelomonocytic leukaemia [J].

Perez, Benoite ;

Kosmider, Olivier ;

Cassinat, Bruno ;

Renneville, Aline ;

Lachenaud, Julie ;

Kaltenbach, Sophie ;

Bertrand, Yves ;

Baruchel, Andre ;

Chomienne, Christine ;

Fontenay, Michaela ;

Preudhomme, Claude ;

Cave, Helene .

BRITISH JOURNAL OF HAEMATOLOGY, 2010, 151 (05) :460-468

[8] Spectrum of mutations in RARS-T patients includes TET2 and ASXL1 mutations [J].

Szpurka, Hadrian ;

Jankowska, Anna M. ;

Makishima, Hideki ;

Bodo, Juraj ;

Bejanyan, Nelli ;

Hsi, Eric D. ;

Sekeres, Mikkael A. ;

Maciejewski, Jaroslaw P. .

LEUKEMIA RESEARCH, 2010, 34 (08) :969-973

← 1 →