A novel application of the Ullmann coupling reaction for the alkylsulfenylation of 2-amino-imidazo[1,2-a]pyridine

被引：31

作者：

Hamdouchi, C ^{[1
]}

de Blas, J ^{[1
]}

Ezquerra, J ^{[1
]}

机构：

[1] Ctr Invest Lilly SA, Madrid 28108, Spain

来源：

TETRAHEDRON | 1999年 / 55卷 / 02期

关键词：

sulfenylation; Ullman coupling; imidazo[1,2-a]pyridines; rhinovirus;

D O I：

10.1016/S0040-4020(98)01052-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Ullmann coupling reaction between the 2-trifluoroacetamido-3-iodo-6-benzoylimididazo[1,2-a]pyridine and dialkyldisulfides (Me, Pr-i) mediated by copper bronze in pyridine, resulted in a novel and highly efficient method for the incorporation of alkylthiol groups at C-3 of this type of heterocyclic system. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：541 / 548

页数：8

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