Fast mapping of protein-protein interfaces by NMR spectroscopy

被引:24
作者
Reese, ML
Dötsch, V
机构
[1] Univ Calif San Francisco, Dept Pharmaceut Chem, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Mol & Cellular Pharmacol, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Grad Grp Biophys, San Francisco, CA 94143 USA
关键词
D O I
10.1021/ja037640x
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Identifying the interface of protein complexes can represent a difficult task in structural biology. Here, we report a method for the fast mapping of interfaces of protein complexes by NMR without the need for the assignments of the proteins involved. Copyright © 2003 American Chemical Society.
引用
收藏
页码:14250 / 14251
页数:2
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