Hormone-sensitive lipase as mediator of lipolysis in contracting skeletal muscle

被引：16

作者：

Donsmark, M

Langfort, J

Holm, C

Ploug, T

Galbo, H

机构：

[1] Univ Copenhagen, Panum Inst, Dept Med Physiol, DK-2200 Copenhagen, Denmark

[2] Univ Copenhagen, Copenhagen Muscle Res Ctr, DK-2200 Copenhagen, Denmark

[3] Polish Acad Sci, Lab Expt Pharmacol, Warsaw, Poland

[4] Lund Univ, Dept Cell & Mol Biol, Sect Mol Signalling, S-22100 Lund, Sweden

[5] Bispebjerg Hosp, Dept Rheumatol, DK-2400 Copenhagen, Denmark

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2005年 / 33卷 / 03期

关键词：

D O I：

10.1097/00003677-200507000-00005

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The authors propose that the enzyme hormone-sensitive lipase (HSL), which is the rate-limiting enzyme for hydrolysis of triacylglycerol in adipocytes, also regulates the intramyocellular triacylglycerol mobilization and is controlled by mechanisms similar to those regulating glycogen phosphorylase. From an exercise perspective, it is fascinating that the primary enzymatic setting allows simultaneous mobilization of all major extramuscular and intramuscular energy stores.

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页码：127 / 133

页数：7

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