One-pot construction of pyrazoles and isoxazoles with palladium-catalyzed four-component coupling

被引：215

作者：

Ahmed, MSM ^{[1
]}

Kobayashi, K ^{[1
]}

Mori, A ^{[1
]}

机构：

[1] Tokyo Inst Technol, Chem Resources Lab, Yokohama, Kanagawa 2268503, Japan

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 20期

关键词：

D O I：

10.1021/ol051841j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four-component coupling of a terminal alkyne, hydrazine (hydroxylamine), carbon monoxide, and an aryl iodide furnishes pyrazole or isoxazole derivatives in the presence of a palladium catalyst. The reaction proceeds at room temperature and an ambient pressure of carbon monoxide in an aqueous solvent system.

引用

页码：4487 / 4489

页数：3

共 21 条

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