Generation of dendritic cells:: role of cytokines and potential clinical applications

被引：11

作者：

Syme, R

Glück, S

机构：

[1] Univ Calgary, Fac Med, Dept Oncol, Tom Baker Canc Ctr, Calgary, AB T2N 4N2, Canada

[2] Univ Calgary, Fac Med, Dept Med, Tom Baker Canc Ctr, Calgary, AB T2N 4N2, Canada

[3] Univ Calgary, Fac Med, Dept Pharmacol & Therapeut, Tom Baker Canc Ctr, Calgary, AB T2N 4N2, Canada

来源：

TRANSFUSION AND APHERESIS SCIENCE | 2001年 / 24卷 / 02期

关键词：

D O I：

10.1016/S1473-0502(01)00005-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Over the last decade there has been great interest in generating populations of antigen presenting cells (APC), which can be exploited to improve immune responses to a variety of diseases including malignancies. Dendritic cells (DC) are an APC population that are easily generated ex vivo using a variety of cytokines. Cytokines can also be used to further manipulate these cells in maturation and function. The following discussion will provide an overview of dendritic cell isolation and generation with a focus on the role cytokines play in this process. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：117 / 124

页数：8

共 51 条

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